Looks like there is a new wrinkle filler on the horizon, and this one is longer lasting. Merz Pharmaceuticals and Fredric Brandt, a dermatologist in New York City, are developing an algie based wrinkle filler that may last up to 12 months—which is comparable to hyaluronic acid fillers like Restylane and Juvéderm, which last six months or more. Called MDF-100, it may also cause less swelling than those fillers. Currently the clinical trials of MDF-100 are awaiting FDA approval. The approval could take over two years, so stay tuned.